The basic idea of the sensor is to use a quartz crystal microbalance to detect the slight increase in mass as a molecule attaches to the sensor surface, and antibodies--part of the body’s immune system--attached to the surface to provide specific binding. In fact, the entire large antibody protein is not necessary for this device; only the single chain variable fragment is sufficient to recognize a specific antigen. In their paper, the researchers describe a sensor that detects Fc receptors, which exist on many cells that play an important role in the immune system.
A research team led by Xiangqun Zeng of the Department of Chemistry is developing new sensors that can detect tiny amounts of important biological molecules.
Created by Brad Roth (firstname.lastname@example.org) on Tuesday, February 22, 2011 Modified by Brad Roth (email@example.com) on Tuesday, February 22, 2011 Article Start Date: Tuesday, February 22, 2011